suramin natural alternative

Quercetin. Ive used it many times, but it is so true. It can heal the intestinal lining in a way that other milks cannot, and then healing the leaky gut syndrome diminishes parts of autism. He truly is speaking much in these days. "Suramin inhibition of growth factor receptor binding and mitogenicity in AKR2B cells." In conjunction with P2X7 that's the main pathway for leaked eATP. 10. I have been taking Sytrinol, 150 mg x 2 daily, for well over 6 months. [3] It is given by injection into a vein. When he had an ME attack (as he called them), he would boil a load of soya beans, which he claimed made him feel much better. antiviral activities [24], and most of these are generally of low toxicity, cheap and 2! I love this Diana, thank you for sharing such good information. The drug is still sold by Bayer under the brand name Germanin. Suramin is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 M), and SirT5 (IC50=22 M). Every time, before I drink, I give the bottle a good shake. Raw Camel Milk can help reverse many parts of autism. Structural Basis For Repurposing A 100-Years-Old Drug Suramin For Treating COVID-19. Enlighten yourself - become aware of what is pulling your health down on a daily basis and what to do about it! You must log in or register to reply here. We make no representations, nor any warranties, nor assume any liability for the content herein; nor do we endorse any particular product, provider, or service. B: May be acceptable. to protect from transmission from the V and to help those who took the V, We are covering everything from vaccines, parenting topics, alternative medicine, and. Thats my guess only. Of-course its going to react. I hope this information helps Luke and any others its relevant too. Just a point of clarification. Did it excellently as well. Most importantly the mysterious seizure-like episode has disappeared. ", 16.Spigelman, Zachary, Amy Dowers, Susan Kennedy, Dennis DiSorbo, Michael O'Brien, Ronald Barr, and Ronald McCaffrey. Yes, those pesky little yellow flowers that seem to love gracing the best of lawns! You can inoculate the tiniest amount of Suramin and reverse Autism! How much would one have to drink to get the effects of reversing Autism? Stresses of all kinds are translated by the cell into graded eATP release. NAC (N-acetyl cysteine) accelerates detoxification and is . "In the '100 Years of Suramin' Study (the following paragraph within the subtitle "(Too) Many Targets") outlines its antidote properties to the spike protein contagion (derived from the mRNA that gives instructions to replicate a spike protein in other . 2 (1991): 155-157. These days I get to enjoy Fennel whenever I so choose, and thats often. Thank you! 6 (1992): 881-889. But of-course they would keep that completely secret and only use it for anyone of their own people who somehow was subjected to the j/a/b. Suramin Definition. (2017) conducted a trial that studied the impact of a single dose of suramin in children with autism and compared their result to a group of children who received the placebo drug (Saline). In summary, a lowered pHe enhanced the activity of all agonists at P2X2 receptors but, with the exception of suramin, not antagonists. Further investigation of the herb reveals a study (Smith . [6] In the United States it can be acquired from the Centers for Disease Control (CDC). Do we know the complete answer? "Antimicrobial activity of the essential oil of young pine shoots (Picea abies L.)." OK, last one, because I'm still trying to understand it. With new variants of SARS-CoV-2 emerging, the COVID-19 pandemic is . You can alsofind me onInstagram,Truth Social(a new free-speech conservative channel), MeWe andTelegram. The information on this website has not been evaluated by the FDA and is not intended to diagnose, treat, prevent, or cure any disease. So I encourage you to play with these things. In other words perfect! I love the way she says that they wouldnt be injecting people unless they already knew what could be done to reverse it. Suramin is, after all, derived from pine needle oil. We are doing this on a trial period to see if this interests our audience. [2], Suramin was made at least as early as 1916. 100 Years of Suramin. http://www.fedup.com.au, Dr Judy explicitly says that pine needle tea will NOT act as anecdote, in fact, it can be toxic and has similar properties to terpentine. As an easily accessible and low-cost natural source, they are 3! Suramin is not extensively metabolized and about 80% is eliminated via the kidneys. One important way that stress-triggered eATP is released occurs through pannexin 1 containing channels in the cell membrane. [7], Suramin is used for treatment of human sleeping sickness caused by trypanosomes. A drug discovered more than 100 years ago may hold the key to combating autism symptoms, according to a study. This has me very excited. et Zucc. Usted recibir 1 2 correos electrnicos al mes (incluyendo los regalos de temporada!) There was some discussion on Phoenix rising about alternatives but it all got a bit confusing for me. It is not found in pine needles and cannot be found in any herbal teas. "After the single dose, it was almost like a roadblock had been released," he said. Regarding our own experiment with natural antipurinergic therapy, we've been trialing Kudzu for the past three weeks and the outcome has been pretty impressive. anyone with more of a brain than me have any ideas? It is more like removing the brakes then pressing the accelerator. **For the Full Spike Protein Protocol (including NAC)to protect from transmission from the V and to help those who took the V,go here. The simplest and most common of weeds are often the very medicine we need to counteract our ill health. Nattokinase (proteolytic enzyme) has a history of being used to, Giant Hyssop or Horsemint (Agastache urtifolia), Wheatgrass and Wheatgrass Juice (the young blades). Weve tried everything else. I think thats an old wives tale. Also, I have written quite a bit about this type of thing in https://marilynjwilliams.com check out the top menu. Pine needles represent a suramin natural alternative, so no great need to wonder where to get suramin. Dr. Jennifer Danials Turpentine and sugar was a bit of a story about a Grand Mother had done for years. Example segmentations of whole T . 16.Spigelman, Zachary, Amy Dowers, Susan Kennedy, Dennis DiSorbo, Michael O'Brien, Ronald Barr, and Ronald McCaffrey. A quick google search was not conclusive of whether Emodin inhibits the Pannexin 1 channel. Here he talks about suramin, which Dr Judy mentioned. current analyst for the pharmaceutical and medical device industries, **For the Full Spike Protein Protocol (including. or Best Offer. (See protocol below). I took some weight recently, and noticed signs of having more estrogens Kudzu is one of the three plants that herbalist Buhner proposes for treating acute symptoms of "neuro-lyme" (and co-infections like Bartonella) - described as a sort of brain inflammation . "Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines." Natural products still play an important role in therapy: between 1981 and 2006, 1,184 new drugs were registered of which 28% were natural products or their derivatives. (especially on purinergic signaling.) This information isn't meant to treat, cure or prevent any disease. Suramin is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor.Suramin efficiently . Coffey Jr, Robert J., Edward B. Leof, Gary D. Shipley, and Harold L. Moses. "Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes." We use cookies to ensure that we give you the best experience on our website. I have never actually taken turpentine it makes me think of the turps used to wash out paint brushes and makes me gag at the thought but I have watched a BioChemist share how to make your own and how to take it. Suramin is manmade and is not a natural product found anywhere in Nature. Ive seen some dandelions in a vegetable patch that were so big I could hardly believe how big they were. The respective distribution of glycosome volumes and for cells treated for 72 h with suramin is shown as a bar graph. ", 21. National Institutes of Health. Antimicrob Agents Chemother 64(2020). So if they sell their homewho knows. The more stress, the more eATP is released. interesting! "Suramin: an anticancer drug with a unique mechanism of action. Sent in accordance with our Privacy Policy. It is still early to say but maybe this will enter the top three interventions. Hosang, Markus. By accessing or using this website, you agree to abide by the Terms of Service, Full Disclaimer, Privacy Policy, Affiliate Disclosure, and Comment Policy. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. Careful clinical trials will be needed over several years at several sites to learn how to use low-dose suramin safely in autism, and to identify drugdrug interactions and rare side effects that cannot currently be predicted. Though, the other day I did hear someone saying that the bark is even more powerful than the needles so maybe thats something you can follow through on. Trypan blue is derived from toluidine, that is, any of several isomeric bases, C14H16N2, derived from, The inhibitory effect of suramin from pine needles on the coronavirus spike protein, Zika and Chikungunya, Making pine needle tea is easy, and only requires fresh, young pine needles and hot water. 2. The first thing we noticed was the improvement in his articulation. 12.Cheng, B., Gao, F., Maissy, E., and Xu, P. (2019). Is Rice Bran Oil an Authentic Health Food. P2X receptors are sensitized by extracellular pH, the most extreme example being the P2X2 subtype where responses to ATP are potentiated under acidic conditions and inhibited under alkaline conditions; pH changes as small as 0.03 units affect the size of the responses (153). By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. And I get the best of both worlds. what about plavix? Within minutes, behavior returned to normal. What a super easy way to give my body Suramin on a regular basis. [2], It is unknown whether it is safe for the baby when a woman takes it while breastfeeding. The study participants in question used 300 milligrams (mg) each day. Naviaux, R.K. & Nguyen, K.V. Its interesting whats going on first she says one thing and then another. Korean Journal of Veterinary Research 33, no. Find many great new & used options and get the best deals for PINE NEEDLE TEA 70GM PINUS SILVESTRIS VITAMIN A C ANTIVIRAL ANTIOXIDANT SURAMIN at the best online prices at eBay! Therefore, before using this product, tell your doctor or pharmacist of all the products you use. [24][25][26][27], 8,8'-{Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonic acid), O=C(Nc1cc(ccc1C)C(=O)Nc3c2c(cc(cc2c(cc3)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c8cccc(NC(=O)Nc7cc(C(=O)Nc6cc(C(=O)Nc5c4c(cc(cc4c(cc5)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)ccc6C)ccc7)c8, InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80), The references used may be made clearer with a different or consistent style of, World Health Organization's List of Essential Medicines, Learn how and when to remove this template message, "Suramin Injection Advanced Patient Information", "Micromedex Detailed Drug Information for the Consumer: Suramin (Injection route)", "Our Formulary Infectious Diseases Laboratories CDC", "Trypanosomiasis, human African (sleeping sickness)", "CDC Infectious Diseases Laboratory: Our Formulary", "Suramin Injection Advanced Patient Information - Drugs.com", "Synthesis and StructureActivity Relationships of Suramin-Derived P2Y, "Inhibition of receptor/G protein coupling by suramin analogues", "International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy", "International union of pharmacology. The regimen commonly prescribed to treat CNS-stage disease involves the use of the trypanocidal drugs suramin and melarsoprol. Thank you! Thank you so much. Dont forget to also check what else you need to do to build your immune system strong it will be more than worth it in the end. Suramin is approximately 99-98% protein bound in the serum and has a half-life of 4178 days average of 50 days; however, the pharmacokinetics of suramin can vary substantially between individual patients. As her life is hounded by the authorities, Im guessing maybe she has had to back-peddle for the sake of her life. [15], The mechanism of action for suramin is unclear, but it is thought that parasites are able to selectively uptake suramin via receptor-mediated endocytosis of drug that is bound to low-density lipoproteins and, to a lesser extent, other serum proteins. "Suramin inhibition of growth factor receptor binding and mitogenicity in AKR2B cells. I wish I could. I do you a concern about the med beds and whether the DNA is actually being reconstructed our is it possible that our DNA is being changed-much the way the jab is changed and damaged. National Library of Medicine. COVID-19 pandemic. https://www.bitchute.com/video/fRmqkRbuaKg6/ [4], Suramin causes a fair number of side effects. Another thing I would recommend is that you visit a naturopath. Any natural medicine with 0.01% of these deaths and side effects would have been pulled from the market immediately. No I am not sure if they need to be heated for the Suramin to be released. Thus, reduction in extracellular pH facilitates P2X2 and P2X2/3 receptors but inhibits P2X1, P2X3, P2X4 and P2X7 receptors (. Outside of that, they believe the governments, the medical profession and even their church leaders would never do anything to harm them. As we know, oil and water do not mix, but this mixes the oil into the water long enough for me to have a drink. Do you have any sense of whether the pine needles are higher than the others in suramin? You must realise too that the medbeds are for good and not evil. Theres an antidote, because these people wouldnt be injecting people unless they knew the answer. "Suramin binds to plateletderived growth factor and inhibits its biological activity. They are SO strict with raw over here. JavaScript is disabled. You cannot continue to consume fake foods, day in and day out, and for your body not to react to it. Janet Ossebaard is one from The Fall of the Cab/al series. The N/W/O and all their minions. please let me know if you try the two you mentioned at the start of this thread. 2) Blocks Il-6 activity and binding to Il-6 receptor in cancer cells, https://www.autismweb.com/forum/viewtopic.php?t=30356&start=20, http://joe.endocrinology-journals.org/content/202/1/141.full.PDF. Suramin can be found in trees, plants and spices which may be growing even in your front lawn! I find one of the best ways to consume a tea that you are not so fond of is to mix it up with one or more other teas. "Antiproliferative effects of suramin on lymphoid cells." I have others mentioned in this post: (This page contains a link to products for purchase. Therefore only 5 boys received suramin by infusion. The same protocol is very useful to protect those concerned with the spike protein transmission FROM those whove been injected. Theres only one way to fight back and thats by joining my FREE newsletter. 9. Press question mark to learn the rest of the keyboard shortcuts. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. "Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer." Ren, P., Zou, G., Bailly, B., Xu, S., Zeng, M., Chen, X., Shen, L., Zhang, Y., Guillon, P., Arenzana-Seisdedos, F., et al. Naviaux Lab, 2023. It prevents the association of heteromeric G proteins and therefore the receptors guanine exchange functionality (GEF). However. A polyanionic compound with an unknown mechanism of action. [10] Suramin uncommonly affects the eyes causing watery eyes, swelling around the eyes, photophobia, and changes or loss of vision. Common side effects include nausea, vomiting, diarrhea, headache, skin tingling, and weakness. By the way, enterovirus can cause gastritis, as well as being linked to ME/CFS. Some places sell powdered camel milk, but I do not think that is as good, and I dont recommend it. Salgado-Benvindo, C. et al. Pure suramin is colorless when dissolved in water or saline as a 10% solution (100 mg/mL). Upon treatment with suramin, median individual glycosome volume increased from 0.0113 to 0.0127 m3 (p 0.037). Ive just stumbled upon upon your site and discovered suramin can be obtained naturally. This has the effect of blocking downstream G protein mediated signaling of various GPCR proteins including rhodopsin, the A1 adenosine receptor, the D2 receptor,[19] the P2 receptor,[20][21] and ryanodine receptors. Journal of ethnopharmacology 35, no. Intramuscular and subcutaneous administration could result in local tissue inflammation or necrosis[citation needed]. But God knew this would happen and provided an answer long before we required it. Government steals your wealth and gives it to themselves in a round about way. 20. The active ingredients in wormwood are toxic to most types of intestinal worms, including Giardia lamblia, a parasite responsible for giardiasis. [3] In regions of the world where the disease is common suramin is provided for free by the World Health Organization (WHO). An extremely good read Fed Up by Sue Dengate. "Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19." Before going, I would want to ascertain she knows about this and could help you with the right dosage. Common side effects of suramin include shock, dizziness, fatigue, headache, loss of consciousness, peripheral nerve damage (neuropathy . Of-course it helps towards keeping my website going. Suramin may cause serious side effects. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Nothing I say on this blog is intended to treat or prevent disease. UPDATE 8/1: Now graphene oxide has been confirmed with irrefutable documentation by former Pfizer employee whistleblower and current analyst for the pharmaceutical and medical device industrieshere. Journal of cellular physiology 132, no. Suramin is a medication used to treat African sleeping sickness and river blindness. Hosang, Markus. 1! According to credible, published research from scientists in Spain from La Quinta Columna, somebut not allinjections, appear to contain high levels of graphene oxide while some appear to be saline placebos. Quoting from our 2017 publication,Like many intravenous drugs, when administered improperly by untrained personnel, at the wrong dose and schedule, without careful measurement of drug levels and monitoring for toxicity, suramin can cause harm. Suramin is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 M). Shared from the research of: Joseph Mercado Article Author: Mike Adams Content Contributor: Natural News Blog Post #1174. Press J to jump to the feed. As you dig really deep, you may be surprised what youll dig up. This also can be made up into a tea. Word is spreading that pine needle tea may offer a solution against covid vaccine "shedding" [] Homeopathic remedies have been praised by advocates for use against viruses and routine ailments. Other P2X receptors are inhibited by H+ ions, so that acidic conditions greatly reduce the potency of extracellular ATP. Have you been tested for this virus? Pine needle tea (obviously nothing poisonous as most pine nuts (from all pine cones ) are edible but some are poisonous she was just covering her ass so to speak ppl have been makin this kinda tea for ages it has high vitamin c and has been used against scurvy for Mariners for 1000s of years, Do you know if the dandylion, star anise, fennel or pine needles have to be in tea or heated to release the suramin? This is a highly concentrated - potent extract that has been created to ensure maximum bioavailability with an easy dosing solution. Now, a new study reviews the potential for curcumin, a natural alkaloid derived from turmeric, and nanosystems to treat COVID-19. It also has an, Trypan blue is so-called because it can kill trypanosomes, the parasites that cause sleeping sickness. Ph-D Boric Vaginal Suppositories 36 Count Each Exp 10/23. Suramin inhibits chikungunya virus replication through multiple mechanisms. Oh my, you made me remember my brother and I when we were young. ", 17.Kathir, Karuppanan Muthusamy, Thallapuranam Krishnaswamy S. Kumar, and Chin Yu. I was excited by these findings too esp as I am also on the autism spectrum. If interested look up her name and look for turpentine video. The natural alternative of Suramin - and the original compound is found in Eastern White Pine (pinus strobus) needles. Naviaux, et al. [4] It is unclear if it is safe when breastfeeding. y puede cancelar su suscripcin en cualquier momento. Suramin as medication is used to treat African sleeping sickness and river blindness. [8][9] It is considered first-line treatment for Trypanosoma brucei rhodesiense, and second-line treatment for early-stage Trypanosoma brucei gambiense, where pentamidine is recommended as first line. We strongly caution against the unauthorized use of suramin.1Homeopathic use of suramin is also illegal and untested. Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143661/, https://news.ycombinator.com/item?id=14458230. Jaw dropping information on all food and the bodies response including learning difficulties. She was healthy and lived a long life taking this faithfully. Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds. & Naviaux, R.K. Optical phenotyping of human mitochondria in a biocavity laser. Emerging microbes & infections 3, e62. It is a symmetric molecule in the center of which lies a urea (NHCONH) functional group. [9], It has been used in the treatment of river blindness (onchocerciasis). Suramin has been used for years to combat African sleeping sickness and river blindness but it has also been found beneficial in slowing the . readily accessible. [10] Suramin causes non-harmful changes in urine during use, specifically making the urine cloudy. "Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines. Its such a dreadful thing that they robbed us of such good food and have destroyed it by pasteurizing and homogenising. The algorithms are set to make it hard for me to be seen there If you want to stay connected, here is one way. 1 (1987): 1-10. Several P2Y12 inhibitors are approved to treat heart disease, but other purinergic receptors are likely to be more important in ASD. 24 (2020): 8331-8347. It likes to be on the cold side of the mountain and doesnt do well on the warmer side. PloS one 9, e91765-e91765. These are proving to be beneficial for people who have taken the jab, or those who come in contain with injected people and find they are experiencing bad symptoms. Sartor, Oliver, Catherine A. McLellan, Charles E. Myers, and M. M. Borner. I've come across two over the counter supplements that inhibit the same purinergic receptors. Consult your own doctor. Thank you for pointing that out. i'm not sure why i'm saying that med, but for some reason it came up in my research around suramin alternatives. [17]:378379[18], It is also used as a research reagent to inhibit the activation of heterotrimeric G proteins in a variety of GPCRs with varying potency. It is considered a ryanodine agent . In addition, pharmaceutical grade suramin is hard to make. Thank you Lizzy for sharing this with us so much appreciated. Xu, H. Eric, Wanchao Yin, Xiaodong Luan, Zhihai Li, Leike Zhang, Ziwei Zhou, Minqi Gao et al. It happened with the first a few days and soon I realized he started to sleep very well without Melatonin. Before you begin treatment with this medicine . It is still early to say but maybe this will enter the top three interventions. Being jabbed with strange substances and experiencing shedding from those individuals has become a reality in this world we live in. Roundup is not sprayed on lawns. Usually after the 2nd fill I can no longer taste the Fennel. ", 9. 15.Mooon, Jeong-jo, Young-bok Han, and Jin-suk Kim. . Journal of cellular biochemistry 29, no. Looks like part of my theories is debunkable - one of the authors did think to check IL-6 and IL-6R before and after exercise in CFS patients (good on him) and found no differences between them and the controls, although he did find "F(2)-isoprostanes were higher (P<0.05) in CFS patients at rest and this difference persisted immediately and 24 h post-exercise." Albulescu, I.C., van Hoolwerff, M., Wolters, L.A., Bottaro, E., Nastruzzi, C., Yang, S.C., Tsay, S.-C., Hwu, J.R., Snijder, E.J., and van Hemert, M.J. (2015). Taken together, the results show that sgp130 may exert an anti-inflammatory effect on microglia and neurons by inhibiting IL-6 binding. 4. and turpentine with sugar taken in a very small dose attracts viral loads to the sugar and the turpentine kills the viral load. On September 5th, the FDA issued a proposed rule rejecting eleven substances nominated by the American Association of Naturopathic Physicians (AANP) and like-minded organizations for use in drug compounding, including curcumin and cesium chloride. Any natural medicine with 0.01% of these deaths and side effects would have been pulled from the market immediately . Yes, it can certainly be found naturally. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. She was annoyed people were being told to make it. (3) This study also says suramin doesn't work well on p2x4. Proceedings of the National Academy of Sciences 83, no. A small, FDA-approved phase 1 clinical trial in 2017 tested suramin's effect on certain "core" autism symptoms in five boys, as compared with five boys given a placebo. Im so thankful that we are entering into a whole new era. "Suramin" is the antidote to the bioweapons and transmission. https://www.biorxiv.org/content/10.1101/2020.10.06.328336v1, 3. It is illegal to import suramin for human use without FDA approval. Happy researching. Today, 100 years later, it is being studied for a variety of applications and treatments . Betsholtz, Christer, Ann Johnsson, Carl-Henrik Heldin, and Bengt Westermark. The intracellular application of 100 mM ethanol did not affect the inhibition of current by 100 mM extracellular ethanol, suggesting that the alcohol inhibition of ATP-gated ion channel function involves the extracellular domain of the receptor.

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